Method for assaying human thymidylate synthase and assay kit

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United States of America Patent

PATENT NO 6569634
SERIAL NO

09530453

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Abstract

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This invention relates to a method for immunologically measuring human thymidylate synthase with an anti-human thymidylate synthase antibody, wherein as the antibody, at least an anti-human thymidylate synthase polyclonal antibody immobilized on an insoluble matrix is used; a method for evaluating sensitivity of cancer cells to a fluoropyrimidine antitumor drug from the results of the measurement by the measuring method; and a human thymidylate synthase measuring kit comprising an insoluble matrix with at least one anti-human thymidylate synthase polyclonal antibody immobilized thereon. By a simple immunological measuring method, human TS in a sample can be measured with high sensitivity.

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Patent Owner(s)

Patent OwnerAddress
MITSUBISHI CHEMICAL MEDIENCE CORPORATION2-8 SHIBAURA 4-CHOME MINATO-KU TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fukushima, Masakazu Hanno, JP 54 376
Hoshino, Nobuhiro Tokyo, JP 7 58
Matsuya, Takeshi Tokyo, JP 6 19
Okabe, Hiroyuki Iruma, JP 22 111

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