Pharmaceutical products comprising endothelial cell precursors

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United States of America Patent

PATENT NO 6569428
SERIAL NO

09228020

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Pharmaceutical products are provided comprising EC progenitors for use in methods for regulating angiogenesis, i.e., for enhancing or inhibiting blood vessel formation, in a selected patient and in some preferred embodiments for targeting an angiogenesis modulator to specific locations. For example, the EC progenitors can be used to enhance angiogenesis or to deliver an angiogenesis modulator, e.g., anti- or pro-angiogenic agents, respectively to sites of pathologic or utilitarian angiogenesis. Additionally, in another embodiment, EC progenitors can be used to induce reendothelialization of an injured blood vessel, and thus reduce restenosis by indirectly inhibiting smooth muscle cell proliferation.

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Patent Owner(s)

Patent OwnerAddress
GENESYS RESEARCH INSTITUTE INC500 BOYLSTON STREET BOSTON MA 02116

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Asahara, Takayuki Arlington, MA 27 458
Isner, Jeffrey M Weston, MA 26 1752

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