Cytotoxic pyrido[2,3,4-ki]acridine derivatives, their preparation and their therapeutic use

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6559161
SERIAL NO

10048340

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The invention provides compounds of formula (I) ##STR1## wherein R.sup.1 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms, a hydroxy group, an alkoxy group having from 1 to 6 carbon atoms, a halogen atom, a nitro group, an amino group, a monoalkylamino group wherein the alkyl moiety has from 1 to 6 carbon atoms, a dialkylamino group wherein each alkyl moiety may be the same or different and each has from 1 to 6 carbon atoms, a dialkoxyamino group wherein each alkoxy moiety may be the same or different and each has from 1 to 6 carbon atoms, an alkanoyalmino group having from 1 to 20 carbon atoms or an alkanesulfonylamino group having from 1 to 6 carbon atoms; R.sup.2 represents a hydrogen atom or an alkyl group having from 1 to 6 carbon atoms; and R.sup.3 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms or an alkoxy group having from 1 to 6 carbon atoms; and pharmaceutically acceptable salts thereof. The compounds exhibit activity against a wide variety of mammalian cancer cell lines.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
UNIVERSIDAD DE BARCELONASPAIN BARCELONA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alvarez, Mercedes Barcelona, ES 5 16
Feliu, Lidia Barcelona, ES 1 0
Fernandez-Puentes, Jose Luis Barcelona, ES 2 0
Garcia, Gravalos Dolores Barcelona, ES 13 52

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation