Recombinant expression of insulin C-peptide
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United States of America Patent
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May 6, 2003
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N/A
app pub date -
Feb 7, 2000
filing date -
Aug 7, 1997
priority date (Note) -
Expired
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Abstract
The present invention provides a method of producing an insulin C-peptide, which comprises expressing in a host cell a multimeric polypeptide comprising multiple copies of the insulin C-peptide, and cleaving the expressed polypeptide to release single copies of the insulin C-peptide. Also provided are nucleic acid molecules, expression vectors and host cells, for use in such a method and the multimeric insulin C-peptide polypeptide expressed and cleaved in such a method.
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