Modulation of cholesteryl ester transfer protein (CETP) activity
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United States of America Patent
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Apr 29, 2003
Issued Date -
N/A
app pub date -
Oct 17, 1997
filing date -
May 1, 1995
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Expired
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Abstract
Conjugates are disclosed comprising a broad range helper T cell epitope portion and a B cell epitope portion from a cholesteryl ester transfer protein (CETP), which conjugates are capable of eliciting an immune response in an individual against the individual's endogenous CETP activity. The conjugates are useful in methods to inhibit CETP activity, to raise serum levels of high density lipoproteins, and to prevent or treat cardiovascular disease, such as atherosclerosis.
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