Tricyclic inhibitors of poly(ADP-ribose) polymerases

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United States of America Patent

PATENT NO 6548494
SERIAL NO

09653184

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Abstract

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Compounds of the formula shown below are poly(ADP-ribosyl)transferase inhibitors: ##STR1## Such compounds are useful as therapeutics in treating cancers and in ameliorating the effects of stroke, head trauma, and neurodegenerative disease.

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Patent Owner(s)

Patent OwnerAddress
CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITEDLONDON NW1 4JL
AGOURON PHARMACEUTICALS10350 NORTH TORREY PINES ROAD LA JOLLA CA 92037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eastman, Brian Walter San Diego, CA 22 81
Kumpf, Robert Arnold Encinitas, CA 16 102
Marakovits, Joseph Timothy Encinitas, CA 18 206
Skalitzky, Donald James San Diego, CA 5 15
Tikhe, Jayashree Girish San Diego, CA 2 16
Webber, Stephen Evan San Diego, CA 15 188

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