Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices
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United States of America Patent
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Apr 15, 2003
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app pub date -
May 18, 2000
filing date -
Nov 12, 1999
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Abstract
The invention relates to a method for lymphoid tissue-specific cell production from hematopoietic progenitor cells in unique, three-dimensional culture devices, in the presence of lymphoreticular stromal cells and in the absence of exogenously added growth factors. The resulting differentiated progeny. The lymphoid tissue-specific cells may be isolated at any sequential stage of differentiation and further expanded. The lymphoid tissue-specific cells also may be genetically altered at any stage of the process.
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