Method for producing solvent-free noncrystalline biologically active substances
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United States of America Patent
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Apr 15, 2003
Grant Date -
N/A
app pub date -
May 11, 2000
filing date -
Nov 28, 1997
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Abstract
Solvent-free noncrystalline bioactive substances are prepared from the corresponding crystalline bioactive substances in an extruder by melting the substances in the extruder under reduced pressure and in the absence of auxiliaries, cooling and comminuting.
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