Dosage forms and methods for oral delivery of progesterone
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United States of America Patent
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Apr 8, 2003
Grant Date -
N/A
app pub date -
Dec 28, 1999
filing date -
Dec 28, 1999
priority date (Note) -
Expired
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Abstract
Provided is an oral dosage form suitable to deliver a combined dosage of progesterone and which upon delivery through the gastrointestinal tract provides a blood concentration of from about 0.1 ng/ml to about 400 ng/ml progesterone; said dosage form comprising a combination that includes (a) a first solid form comprising from about 25 mg to about 500 mg micronized progesterone in a solid polyethylene glycol carrier having an average molecular weight of from about 1000 to 10,000 and constituting at least about 30% of said first solid form; and (b) a second solid form comprising an estrogen.
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