Method of producing porous tablets with improved dissolution properties
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United States of America Patent
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Apr 8, 2003
Grant Date -
Sep 26, 2002
app pub date -
Jan 11, 2001
filing date -
Jan 11, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method of producing a fast-dissolving pharmaceutical delivery device of moderate strength. The delivery device is a fully formed tablet composed of readily available sugars, strength polymers and a volatilizable excipient along with an active ingredient and optional flavorings. The tablet as made will disintegrate in an aqueous medium such as saliva in under 15 seconds, making mastication unnecessary or at least requiring only one or two bites on the tablet. Essential to the invention is the easily obtainable particle size ranges of the sugars and the volatilizable excipient which promotes optimum release and tablet strength. The invention also allows for effective taste masking of the active ingredient with standard particle coating techniques.
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