Preparations comprising a fluorocarbon or highly fluorinated compound and a lipophilic/fluorophilic organic compound, and their uses
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Mar 4, 2003
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N/A
app pub date -
Jun 2, 2000
filing date -
Jul 17, 1991
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Expired
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Abstract
Fluorocarbon emulsions comprising a stabilizing, particle size controlling fluorophilic/hydrophilic compound which can have the formula R.sub.F.sup.1 --W--R.sub.H.sup.1 (I) wherein R.sub.F.sup.1 is a linear, branched or cyclic C.sub.2-14 fluorocarbon group; R.sub.H.sup.1 is a linear, branched or cyclic C.sub.2-18 saturated or unsaturated hydrocarbon group; and W is absent or is a bivalent species chosen from the group consisting of --O--, --S--, or various fluorinated structures. Use of the fluorophilic/lipophilic compound in the dispersions of the invention provides stable particle size and efficient emulsification. The dispersions of the invention can comprise biologically useful additive and can be used for various purposes, as oxygen carriers, contrast agents, or diagnostic agents.
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