Human neuronal nicotinic acetylcholine receptor compositions and methods employing same
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United States of America Patent
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Feb 25, 2003
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N/A
app pub date -
Jun 7, 1996
filing date -
Jun 7, 1995
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Expired
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Abstract
Nucleic acid molecules encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing the nucleic acid molecules, and methods for producing alpha and beta subunits are provided. In particular, nucleic acid molecules encoding .alpha..sub.6 subunits and molecules encoding .beta..sub.3 subunits of human neuronal nicotinic acetylcholine receptors are provided. In addition, combinations of a plurality of subunits, such as one or more of .alpha..sub.1, .alpha..sub.2, .alpha..sub.3, .alpha..sub.4, .alpha..sub.5, .alpha..sub.6 and/or .alpha..sub.7 subunits in combination with one or more of .beta..sub.3 subunits or such as one or more of .beta..sub.2, .beta..sub.3 and/or .beta..sub.4 subunits in combination with an .alpha..sub.6 subunit are provided.
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