Inhibitors of the ICE/ced-3 family of cysteine proteases
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United States of America Patent
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Feb 4, 2003
Grant Date -
N/A
app pub date -
Jan 13, 2000
filing date -
Jan 13, 2000
priority date (Note) -
Expired
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Abstract
This invention s directed to novel oxamyl dipeptide ICE/ced-3 family inhibitor compounds having the following structure: ##STR1## wherein A, B, R, R.sub.1, p and q are as defined herein. The invention s all directed to pharmaceutical compositions containing one or more of thee compound, as well as to the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that to undergo a transplantation procedure.
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