Photoactivatable nucleic acids
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United States of America Patent
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Jan 14, 2003
Issued Date -
N/A
app pub date -
Feb 24, 1998
filing date -
Aug 15, 1997
priority date (Note) -
Expired
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Abstract
A photoactivatable nucleic acid derivative composition in which one or more photoreactive group(s) are bound to a natural or synthetic nucleic acid. The photoreactive groups can be bound to the nucleic acid before, during or after its formation, and can thereafter be activated in order to attach the nucleic acid to another molecule, e.g., to the surface of a solid support. Also described is a method of preparing such a composition, and a method of using such a composition to attach the nucleic acid to a another molecule, such as that provided by the surface of a substrate used to prepare a nucleic acid chip by photolithographic techniques.
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