Optimized antisense oligonucleotides complementary to DNA methyltransferase sequences
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United States of America Patent
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Jan 14, 2003
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app pub date -
May 22, 2000
filing date -
Feb 3, 1998
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Abstract
The invention provides optimized antisense oligonucleotides complementary to the DNA methyltransferase gene or its RNA transcript. The invention further provides methods for using such antisense oligonucleotides as analytical and diagnostic tools, as potentiators of transgenic plant and animal studies and gene therapy approaches, and as potential therapeutic agents.
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