Plasminogen activator as an anti-inflammatory agent

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United States of America Patent

PATENT NO 6497877
SERIAL NO

09355522

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Abstract

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Plasminogen activator acts as an anti-inflammatory agent by inhibiting generation of superoxide anion by a mechanism that is not related to L-arginine, is not dependent on thrombolytic activity, and is not a function of oxygen free radical scavenging. Moreover, in in vivo models of inflammation, treatment with plasminogen activator reduces edema without inhibiting neutrophil infiltration in in vivo models of inflammation.

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Patent OwnerAddress
UNIVERSITY TECHNOLOGY CORPORATION3101 IRIS AVENUE SUITE 250 BOULDER CO 80301

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hybertson, Brooks M Boulder, CO 4 52
McCord, Joe M Denver, CO 2 3
Repine, John E Englewood, CO 16 442
Stringer, Kathleen A Denver, CO 3 11

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