Biologically active analogs of discodermolide
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Dec 17, 2002
Grant Date -
Dec 6, 2001
app pub date -
Feb 28, 2001
filing date -
Mar 1, 2000
priority date (Note) -
Expired
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Abstract
The subject invention provides novel compositions of biologically active discodermolide compounds which can advantageously be used for immunomodulation and/or treating cancer. The compounds of the subject invention have utility for use in the treatment of cancer, as tubulin polymerizers and as microtubule stabilization agents. The present invention also pertains to the identification of regions of the discodermolide molecule which are responsible for certain aspects of the bioactivity of discodermolide compounds.
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