2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
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United States of America Patent
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Dec 17, 2002
Grant Date -
May 9, 2002
app pub date -
May 21, 2001
filing date -
Oct 29, 1999
priority date (Note) -
Expired
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Abstract
4-substituted cyclohexanes substituted in the 1-position with imidazopyridine either directly or through a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkenyl, C.sub.1 -C.sub.4 alkynyl, C.sub.1 -C.sub.4 alkoxy, amino, aminoC.sub.1 -C.sub.4 alkyl, hydroxyC.sub.1 -C.sub.4 alkyl, carbonyl, cycloC.sub.3 -C.sub.6 alkyl or aminocarbonyl chain are effective as NMDA NR2B antagonists useful for relieving pain.
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