Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration

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United States of America Patent

PATENT NO 6495023
SERIAL NO

09793025

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Disclosed are methods using neutral red to mediate the interconversion of chemical and electrical energy. Electrically reduced neutral red has been found to promote cell growth and formation of reduced products by reversibly increasing the ratio of the reduced:oxidized forms of NAD(H) or NADP(H). Electrically reduced neutral red is able to serve as the sole source of reducing power for microbial, cell growth. Neutral red is also able to promote conversion of chemical energy to electrical energy by facilitating the transfer of electrons from microbial reducing power to a fuel cell cathode.

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Patent Owner(s)

Patent OwnerAddress
MICHIGAN BIOTECHNOLOGY INSTITUTE3900 COLLINS ROAD LANSING MI 48910

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jain, Mahendra K Lexington, KY 14 824
Shin, Hyoun S Lansing, MI 3 306
Zeikus, Gregory J Okemos, MI 3 305

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