Examination of biological tissue by monitoring one or more solutes

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United States of America Patent

PATENT NO 6493565
SERIAL NO

08849203

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Abstract

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This invention is a scheme for monitoring a solute in a biological system comprising the steps of delivering light into a biological system (12) containing a solute, the light having a wavelength selected to be in a range wherein the solute is substantially non-absorbing; detecting at least first and second portions of the delivered light (16, 18, 20), the first portion having traveled through the biological system along one or more paths characterized by a first average path length, and the second portion having traveled through the biological system along one or more as characterized by a second average path length that is greater than the first average path length; and comparing the first and second portions of the delivered light to monitor concentration of the solute in the biological system. Also described are schemes for monitoring low molecular weight polyhydroxy solutes, generally sugars (mannitol, fructose, sucrose, glucose, sorbitol), alcohols (methanol, ethanol, propanediol), and electrolytes (sodium, potassium, magnesium, calcium, and chloride ions).

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Patent Owner(s)

Patent OwnerAddress
NON-INVASIVE TECHNOLOGY INCPHILADELPHIA PA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chance, Britton Marathon, FL 83 8196
Liu, Hanli Arlington, TX 13 411

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