Racemic thioesters for production of polyketides

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United States of America Patent

PATENT NO 6492562
SERIAL NO

09492733

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Abstract

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Facile methods for preparing diketide and triketide thioesters are disclosed. The resulting thioesters may be used as intermediates in the synthesis of desired polyketides, and may contain functional groups which ultimately reside in side chains on the resulting polyketide and thus can be used further to manipulate the polyketide so as form derivatives. The polyketides produced may also be tailored by glycosylation, hydroxylation and the like. New polyketides and their derivatives and tailored forms are thereby produced.

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Patent Owner(s)

Patent OwnerAddress
KOSAN BIOSCIENCES INC3832 BAY CENTER PLACE HAYWARD CA 94545

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ashley, Gary Alameda, CA 55 477
Burlingame, Mark A San Francisco, CA 6 25
Chan-Kai, Isaac C Hayward, CA 3 19

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