4,5-diaryl-3(2H)-furanone derivatives as cyclooxygenase-2 inhibitors
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United States of America Patent
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Dec 10, 2002
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app pub date -
Nov 27, 2001
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Apr 14, 1999
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Abstract
The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.
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