Methods and compositions for producing viral particles

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United States of America Patent

PATENT NO 6489142
SERIAL NO

09700422

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention concerns methods and constructs for producing retroviral particles, in vitro, ex vivo or in vivo. It also concerns the use of said methods and constructs for transferring nucleic acids into cells. More particularly, the invention concerns a composition comprising the whole set of genetic elements required for constituting a retroviral particle, incorporated in one or several recombinant adenoviruses defective for all or part of the regions E1 and E4 at least (adenoviral/retroviral chimeric vectors).

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Patent Owner(s)

Patent OwnerAddress
AVENTIS PHARMA S A20 AVENUE RAYMOND ARON ANTONY CEDEX FRANCE 92165
GENOPOIETIC22 RUE ESQUIROL PARIS 75013

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Klatzmann, David Paris, FR 48 550
Perricaudet, Michel Ecrosnes, FR 60 654
Salzmann, Jean-Loup Paris, FR 11 254
Torrent, Christophe Paris, FR 3 113
Yeh, Patrice Gif sur Yvette, FR 45 1510

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