Anti-HIV infection agents and method for treating HIV infection
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United States of America Patent
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Sep 24, 2002
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app pub date -
Jun 20, 2001
filing date -
Dec 24, 1998
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Abstract
The present invention relates to agents for anti-HIV infection, which contain, as an active ingredient, at least one photosensitizing dye selected from the group consisting of the compounds of the formulae (I) and (II): ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different and each represents alkyl group having 1 to 4 carbon atoms, R.sub.4, R.sub.5 and R.sub.6 are the same or different and each represents alkyl group having 5 to 10 carbon atoms, and X.sup.- represents a physiologically acceptable monovalent anion. The present invention also relates to a method for treating or preventing HIV infection diseases, which includes administering the photosensitizing dye. A daily dose of the photosensitizing dye is usually 2 to 100 .mu.g, and preferably 5 to 40 .mu.g, per kg body weight. Administration of the photosensitizing dye to HIV infected subjects leads to improvement or cure of the symptoms of AIDS related complex and increase in CD4-positive lymphocytes, which is effective for the treatment of HIV infection diseases.
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