3'-exonuclease, production and use thereof

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United States of America Patent

PATENT NO 6451307
SERIAL NO

09719787

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a poly(A)-specific 3'-exonuclease activity which can be obtained by chromatographically purifying a crude extract of animal or human cells and to its use for deadenylating 3'-poly(A) tails of nucleic acids and as a pharmaceutical or diagnostic agent, or for identifying functional interactors.

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Patent Owner(s)

Patent OwnerAddress
AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG65926 FRANKFURT

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Astrom, Jonas Uppsala, SE 5 5
Gallert, Karl-Christian Karben, DE 2 0
Huls, Christoph Wackernheim, DE 6 86
Martinez, Javier Uppsala, SE 25 307
Neumann, Thomas Frankfurt, DE 69 715
Ren, Yanguo Uppsala, SE 1 0
Thuresson, Ann-Charlotte Uppsala, SE 1 0
Virtanen, Anders Uppsala, SE 7 17

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