Pharmaceutical compositions comprised of stabilized peptide particles

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United States of America Patent

PATENT NO 6447806
SERIAL NO

09668889

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Particles of a substantially water insoluble biologically active substance, such as Cyclosporin, are loaded with a charged glyceryl ester as an electrostatic stabilizer which imparts to the particles a zeta potential and having an active substance:stabilizer weight ratio of 1:1 to 400:1 and an average particle diameter of 1 nanometer to 10 micrometers. Compositions having such particles are found to be useful delivery systems.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS AG (FORMERLY SANDOZ LTD )LICHTSTRASSE 35 BASEL 4056

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gassmann, Peter Weil, DE 1 55
Sucker, Heinz Basel, CH 3 128

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