Process for the preparation of radiopharmaceuticals
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United States of America Patent
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Sep 10, 2002
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app pub date -
Oct 28, 1997
filing date -
Oct 29, 1996
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Abstract
Process for the preparation of radiohalogenated radiopharmaceuticals by an electrophillic substitution, preferably halogenodestannylation reactions, by the reaction of an organometallic substituted precursor, preferably a trialkyl tin substituted precursor, with a radioactive halogen, preferably a radioactive iodine, astatine or bromine composition, in the presence of a catalytically effective amount of an anion selected from the group consisting of bromide, chloride and nitrite anion in an acid medium with an oxidizing agent.
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