Methods of using inhibitors of cyclophilin rotamase activity to affect neurological activity

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United States of America Patent

PATENT NO 6444643
SERIAL NO

09321762

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Abstract

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This invention relates to the method of using neurotrophic cyclophilin inhibitor compounds having an affinity for cyclophilin-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.

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Patent Owner(s)

Patent OwnerAddress
GUILFORD PHARMACEUTICALS INC6611 TRIBUTARY STREET BALTIMORE MD 21224

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hamilton, Gregory S Catonsville, MD 129 1221
Snyder, Solomon H Baltimore, MD 48 772
Steiner, Joseph P Finksburg, MD 91 894

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