Autologous fibrin sealant and method for making the same

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United States of America Patent

PATENT NO 6444228
SERIAL NO

09063338

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Abstract

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In general, the present invention relates to a two-phase method for forming an autologous bioadhesive sealant composition or fibrin glue wherein all of the blood components for the bioadhesive sealant are derived from a patient to whom the bioadhesive sealant will be applied. First, a platelet rich plasma and a platelet poor plasma are formed by centrifuging a quantity of anticoagulated whole blood that was previously drawn from the patient. The platelet rich plasma and platelet poor plasma are then divided into two portions. To the first portion, which is used in phase-one, a compound that reverses the effect of the anticoagulant is added, and a clot is allowed to form. The clot is then triturated and the resulting serum, containing autologous thrombin, is collected. The serum obtained from phase-one is then mixed with the second portion of the platelet rich plasma or platelet poor plasma, used in phase-two, to form the bioadhesive sealant of the present invention.

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Patent Owner(s)

Patent OwnerAddress
ARTERIOCYTE MEDICAL SYSTEMS INC11000 CEDAR AVENUE SUITE 270 CLEVELAND OH 44106

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baugh, Robert F Parker, CO 37 1327
Johnston, Julie S Highlands Ranch, CO 9 386
Lim, Lisa M Aurora, CO 10 463
Rivera, John G Aurora, CO 14 668

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