Process for preparing retiferol derivatives

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United States of America Patent

PATENT NO 6437142
SERIAL NO

09817465

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A new process prepares retiferol derivatives of formula I: ##STR1## wherein A is --C.ident.C-- or --CH.dbd.CH--, and R.sup.1 and R.sup.2 are independently of each other lower alkyl or lower perfluoroalkyl, one version couples ketones of formula II with compounds of formula III. A second version couples phosphinoxides of formula IV with aldehydes of formula V. Compounds of formula I are useful in the treatment or prevention of hyperproliferative skin diseases and for reversing the conditions associated with photodamage.

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Patent Owner(s)

  • BASILEA PHARMACEUTICA AG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hilpert, Hans Reinach, CH 107 481
Wirz, Beat Reinach, CH 34 217

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