Diacyl-substituted guanidines, a process for their preparation, their use as medicine or diagnostic aid, and medicine containing them
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United States of America Patent
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Aug 20, 2002
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N/A
app pub date -
Apr 18, 1997
filing date -
Aug 24, 1993
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Abstract
Diacyl-substituted guanidines of the formula I ##STR1## are described where X(1) and X(2) are ##STR2## as defined herein. The compounds are suitable for use as antiarrhythmic pharmaceuticals possessing a cardioprotective component for the prophylaxis and treatment of infarction and for the treatment of angina pectoris, in connection with which they also inhibit or strongly reduce, in a preventitive manner the pathophysiological processes associated with the genesis of ischemically induced damage, in particular associated with the elicitation of ischemically induced cardiac arrhythmias.
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