Erythromycin derivatives, a process for their preparation and their use as medicaments
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United States of America Patent
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Aug 13, 2002
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N/A
app pub date -
Jul 8, 1999
filing date -
Jul 9, 1998
priority date (Note) -
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Abstract
The invention relates to compounds of the formula (I) ##STR1## in which R represents a radical (CH.sub.2).sub.m O.sub.n (X)YAr in which m represents the number 0 or 1, n represents the number 0 or 1, X represents a radical (NH).sub.a, CH.sub.2 or SO.sub.2, where a represents the number 0 or 1, Y represents a radical (CH.sub.2).sub.b --(CH.dbd.CH).sub.c --(CH.sub.2).sub.d, where c=0 or 1 and b+c+d .ltoreq.8, Z represents a hydrogen or halogen atom, Ar represents an optionally substituted aryl or heteroaryl radical and W represents a hydrogen atom or an acyl radical, and their acid addition salts. The compounds of the formula (1) have antibiotic properties.
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