Process for producing granules containing angiotensin-converting enzyme inhibiting peptides

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United States of America Patent

PATENT NO 6428812
SERIAL NO

09231449

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Abstract

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Granules and tablets for oral administration, containing angiotensin-converting enzyme inhibiting peptides and treated whey with a mixing fluid bed processor, wherein said whey is obtained from lactic acid fermentation liquid. The granules have properties of narrow particle distributions, low moisture absorption, and heavy specific gravity, as well as high free flowing. A process is also provided for producing the granules by the steps of: a) onto seed granules obtained in an earlier operation in a mixing fluid bed processor, spraying purified whey of lactic acid fermentation liquid to form preliminary granules; b) treating the preliminary granules thus obtained to reduce particle size in a size reduction mill; c) returning the treated powder to the mixing fluid bed processor, and, d) spraying additional purified whey onto the returned powder in the mixing fluid bed processor to form granules, while fluidizing the said powder.

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Patent Owner(s)

Patent OwnerAddress
CALPIS CO LTD20-3 EBISU-NISHI 2-CHOME SHIBUYA-KU TOKYO 150-0021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kitamura, Shuji Tokyo, JP 36 589
Ueyama, Takashi Kanagawa-ken, JP 13 35

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