Oligoribonucleotide and ribozyme analogs with terminal 3'--3' and/or 5'--5' linkages
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United States of America Patent
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Jul 16, 2002
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N/A
app pub date -
Apr 14, 1998
filing date -
Sep 24, 1992
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Expired
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Abstract
The invention relates to oligoribonucleotide analogs with terminal 3'--3' and/or 5'--5' internucleotide linkages. This modification stabilizes the molecules altered in this way, including ribozymes, without adversely altering their properties, including, where appropriate, catalytic activities.
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