Sulphur derivatives with a retroamide bond as endothelin-converting enzyme inhibitors
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United States of America Patent
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Jul 16, 2002
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N/A
app pub date -
Oct 30, 1998
filing date -
Mar 4, 1996
priority date (Note) -
Expired
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Abstract
Products of formula (1), wherein R.sub.1 is particularly phonyl or biphenyl optionally substituted by halogen n1 and n2 are 0 or 1, R.sub.2 is particularly hydrogen or methyl substituted by phenyl, which may in turn be substituted, and A is partcularly carboxy or alkyl substituted particularly by phenoxy, as well as all isomers and organic and inorganic base addition salts therof, are disclosed. ##STR1##
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