8-(heterocyclylmethyl)quinoline derivatives for treating urinary incontinence

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United States of America Patent

PATENT NO 6413984
SERIAL NO

09890526

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Abstract

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The invention concerns compounds of formula (I) wherein: A represents either a hydrogen atom or a hydroxyl group; B represents a pyrrolidin-2-yl (D) or 2-piperidyl (E), B capable of being substituted by one or two R.sub.5 groups; R.sub.1 represents a hydrogen atom, a C.sub.1 -C.sub.6 alkyl, a C.sub.2 -C.sub.6 alkenyl, a C.sub.1 -C.sub.2 perfluoroalkyl or a C.sub.1 -C.sub.6 fluoroalkyl group; R.sub.2, R.sub.3 or R.sub.4, independently of one another, represent a hydrogen atom, a C.sub.1 -C.sub.6 alkyl, group or a C.sub.2 -C.sub.6 alkenyl group, or R.sub.1 and R.sub.2 can together form a C.sub.1 -C.sub.6 alkylene chain, or a C.sub.3 -C.sub.6 alkenylene chain; R.sub.5 represents a C.sub.1 -C.sub.6 alkyl group, and R.sub.6 represents a hydrogen atom, a C.sub.1 -C.sub.6 alkyl group, a C.sub.2 -C.sub.6 alkenyl group, C.sub.3 -C.sub.6 cycloalkyl, C.sub.3 -C.sub.6 cycloalkenyl or a benzyl. Said compounds have therapeutic applications ##STR1##

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Patent OwnerAddress
SANOFI-SYNTHELABO174 AVENUE DE FRANCE F-75013 PARIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bovy, Philippe R Mareil Marly, FR 35 245
Braun, Alain Boulogne Billancourt, FR 11 97
Philippo, Christophe Reuil Malmaison, FR 19 279

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