Diagnosis for mutant APC by immunoassay

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United States of America Patent

PATENT NO 6413727
SERIAL NO

08449731

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Abstract

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A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. These results suggest that APC is a tumor suppressor.

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Patent Owner(s)

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THE JOHNS HOPKINS UNIVERSITY3400 N CHARLES STREET BALTIMORE MD 21218

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albertsen, Hans Salt Lake City, UT 17 447
Anand, Rakesh Sandbach, GB 15 488
Carlson, Mary Salt Lake City, UT 9 482
Groden, Joanna Salt Lake City, UT 12 485
Hedge, Philip John Winsford, GB 7 360
Joslyn, Geoff Salt Lake City, UT 9 482
Kinzler, Kenneth Baltimore, MD 28 964
Markham, Alexander Fred Crewe, GB 17 337
Nakamura, Yusuke Tokyo, JP 416 3218
Thliveris, Andrew Salt Lake City, UT 8 440
Vogelstein, Bert Baltimore, MD 338 7135
White, Raymond L Salt Lake City, UT 16 527

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  • 43 Citation Count
  • G01N Class
  • 90.37 % this patent is cited more than
  • 23 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges6711414762289747492313986501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +05010015020025030035040045050055060065070075080085090095010001050110011501200

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