Compositions having neuroprotective and analgesic activity
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United States of America Patent
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Jun 25, 2002
Issued Date -
N/A
app pub date -
Apr 3, 2000
filing date -
Sep 9, 1994
priority date (Note) -
Expired
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Abstract
Compounds of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are alkyl of 1-8 carbons have been shown to have both neuroprotective and analgesic activities. The compounds of the invention may be used in treatment of conditions that would normally result in neuronal damage, including those arising on account of cerebral ischemia/hypoxia or increase in intracranial pressure such as neoplasms, stroke, meningitis or trauma and for treatment of pain. Compositions of the invention can also be useful for treatment of toxin-related damage such as drug over-dose or exposure to toxins in the environment.
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