Self-assembling genes, vectors and uses thereof
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United States of America Patent
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Jun 25, 2002
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N/A
app pub date -
Aug 26, 1999
filing date -
Feb 28, 1997
priority date (Note) -
Expired
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Abstract
The invention relates to a method for directing the self-assembly of a gene or gene assembly having three and preferably six or more fragments in a directionally and spatially ordered fashion to produce a gene, gene vector or large nucleic acid molecule. The method can be used to create libraries, such as combinatorial libraries. In another embodiment of the invention a vector is described for the incorporation and screeming of endogenous mouse promoter elements for the identification of cell-specific promoters.
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