Lysoganglioside derivatives
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United States of America Patent
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Jun 18, 2002
Issued Date -
N/A
app pub date -
Jun 30, 1994
filing date -
Dec 2, 1988
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Expired
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Abstract
Novel N-acyl-lysogangliosides obtained from gangliosides by deacyation of the ceramide group, wherein the acyl group is derived from an aliphatic acid having from 2 to 24 carbon atoms, substituted by one or more polar groups. The N-acyl-lysogangliosides of the invention exhibit an inhibiting action on protein-kinase C activation and, thus, can be utilized in therapies for various pathologies of the nervous system.
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