Ternary ligand complexes useful as radiopharmaceuticals
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United States of America Patent
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Jun 11, 2002
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May 28, 1997
filing date -
May 28, 1997
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Abstract
The present invention provides novel radiopharmaceuticals useful for imaging the heart, brain, lungs, liver or kidneys, kits useful for preparing the radiopharmaceuticals, and methods of imaging the heart, brain, lungs, liver or kidneys in a patient in need of such imaging. The radiopharmaceuticals are comprised of technetium or rhenium radionuclide complexes of a ternary ligand system: one hydrazido or diazenido ligand, one aminoalcohol ligand, and one pi-acid ligand selected from phosphines, arsines, and imine nitrogen-containing heterocycles. The radiopharmaceuticals have the formula, ML.sup.1 L.sup.2 L.sup.3, wherein the variables are as defined herein.
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