Oxathiazolidinyl pyridines
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United States of America Patent
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May 28, 2002
Issued Date -
N/A
app pub date -
Jul 12, 2000
filing date -
Jun 3, 1994
priority date (Note) -
Expired
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Abstract
Compounds having the formula R.sup.5 O--A--NR.sup.4 --R.sup.2 (V) where R.sup.2 is a heteroaryl group linked to the remainder of the molecule via a carbon atom adjacent a nitrogen atom and R.sup.4 and R.sup.5 are both hydrogen atoms or together represent --SO-- or --SO.sub.2 -- and A is C.sub.2 -C.sub.4 alkylene optionally substituted by one or more lower alkyl groups are novel intermediates in the preparation of pharmaceutically useful piperazine derivatives as end compounds. The compounds having formula V where R.sup.4 and R.sup.5 are hydrogen may be prepared by a rearrangement of a compound having the formula (VI). R.sup.2 O--A--NH.sub.2 (VI)
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