Methods for detecting membrane derived caspase activity and modulators thereof
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United States of America Patent
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May 21, 2002
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N/A
app pub date -
Mar 5, 1999
filing date -
Mar 5, 1999
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Expired
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Abstract
Provided are methods for detecting membrane derived apoptotic activity. In one embodiment, the present invention provides methods for identifying membrane derived caspase activity. In other embodiments, drug discovery methods are provided for screening compounds that inhibit or enhance membrane derived caspase activity. In the various embodiments, heavy membrane fractions are utilized for the screening methodologies described herein.
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