Leukocyte homing modulation

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United States of America Patent

PATENT NO 6387884
SERIAL NO

08336417

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Abstract

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Novel methods and compositions are provided for modulating homing of leukocytes, particularly lymphocytes, where the compounds are cross-reactive with Neu5Ac2-3Gal.beta.1-X[Fuc.alpha.1-y]GlcNAc, where one of x and y is three and the other is four. These compounds may be administered to a host associated with inflammation, to avoid the deleterious effects of leukocyte infiltration.

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Patent Owner(s)

Patent OwnerAddress
GLYCOMIMETICS INC9708 MEDICAL CENTER DR ROCKVILLE MD 20850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berg, Ellen L Fremont, CA 23 949
Butcher, Eugene C Portola Valley, CA 36 1004
Magnani, John L BioCarb Incorporated 300 Professional Dr., Suite 100, Gaithersburg, MD 20879 95 1078

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