Assay for a regulator of cell cycle progression
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United States of America Patent
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May 14, 2002
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N/A
app pub date -
Nov 14, 2000
filing date -
Sep 30, 1996
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Expired
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Abstract
The present invention provides nuclear localisation signals derived from the DP-3 and E2F-1 transcription factors and the use of these signals in assays for regulators of cell cycle progression. Such assays involve using the signals to direct a marker gene to the nucleus and determining whether the nuclear localisation of the marker is disrupted by the presence of a putative regulator.
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