Heterocycles useful in the treatment of benign prostatic hyperplasia
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United States of America Patent
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May 7, 2002
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N/A
app pub date -
Oct 9, 1998
filing date -
Oct 9, 1997
priority date (Note) -
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Abstract
This invention relates a to a series of heterocyclic substituted piperazines of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention selectively inhibit binding to the .alpha.-1a adrenergic receptor, a receptor which has been implicated in benign prostatic hyperplasia. As such the compounds are potentially useful in the treatment of this disease.
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