HIV integrase inhibitors
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United States of America Patent
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Apr 30, 2002
Grant Date -
N/A
app pub date -
Jun 1, 1999
filing date -
Jun 3, 1998
priority date (Note) -
Expired
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Abstract
Certain six-membered aromatic and heteroaromatic-dioxobutyric acid derivatives are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
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