Carboxamidothiazole derivatives, preparation, pharmaceutical compositions containing them
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Apr 30, 2002
Grant Date -
N/A
app pub date -
Jun 2, 2000
filing date -
Sep 19, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to cholecystokinin (CCK)-agonist substituted thiazoles of formula: ##STR1## in which R.sub.1 is a substituted phenyl group, R.sub.2 is a group chosen from CH.sub.2 --R.sub.7, (CH.sub.2).sub.2 --R.sub.7, S--CH.sub.2 --R.sub.7, CH.sub.2 --S--R.sub.7 and (C.sub.5 -C.sub.8)alkyl with R.sub.7 being a (C.sub.5 -C.sub.7)cycloalkyl group, and R.sub.3 is a group ##STR2## with R.sub.8 being a group (CH.sub.2).sub.n R.sub.15 or ##STR3## and R.sub.15 being COOH or COO(C.sub.1 -C.sub.4)alkyl. The invention also relates to a process for the preparation of the pharmaceutical compositions containing them and to their uses for the preparation of medicines.
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