Chip-based isothermal amplification devices and methods

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United States of America Patent

PATENT NO 6379929
SERIAL NO

08974738

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are methods and compositions for isothermal amplification of nucleic acids in a microfabricated substrate. Methods and compositions for the analysis of isothermally amplified nucleic acids in a microfabricated substrate are disclosed as well. The microfabricated substrates and isothermal amplification and detection methods provided are envisioned for use in various diagnostic methods, particularly those connected with diseases characterized by altered gene sequences or gene expression.

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Patent Owner(s)

Patent OwnerAddress
BECTON DICKINSON AND COMPANY1 BECTON DRIVE MC110 FRANKLIN LAKES NJ 07417-1880

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beyer, Jr Wayne F Bahama, NC 5 637
Burke, David T Ann Arbor, MI 8 1335
Burns, Mark A Ann Arbor, MI 57 3414
DeNuzzio, John D Chapel Hill, NC 19 5050
Johnson, Brian N Ann Arbor, MI 13 1716

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  • 603 Citation Count
  • C12P Class
  • 96.30 % this patent is cited more than
  • 23 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges2421047201310533211301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0102030405060708090100110120130140150160170180190200210220230

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