Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production

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United States of America Patent

PATENT NO 6376483
SERIAL NO

09320731

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Abstract

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Bacteriochlorins and bacteriopurpurins useful for photodynamic therapy and methods for their manufacture are described herein. Methods for producing the claimed compounds include contacting meso-diacrylate porphyrin precursors with a solvent and a base catalyst at sufficient temperature and time to yield the desired conversion. Reduced bacteriochlorins can be produced by contacting unsaturated bacteriochlorins or bacteriopurpurins with a hydrogenation catalyst and hydrogen. These methods provide new routes for synthesizing bacteriochlorins and bacteriopurpurins from symmetrical and asymmetrical meso-diacrylate porphyrins.

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Patent Owner(s)

Patent OwnerAddress
MIRAVANT PHARMACEUTICALS INC7408 HOLLISTER AVENUE SANTA BARBARA CA 93117

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Robinson, Byron C Santa Barbara, CA 15 326

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